When can you participate?
You can participate in this study if you are currently between 8 and 10 weeks pregnant of one baby and you are at risk for spontaneous preterm labor because either:
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You had a sPTB during a previous pregnancy, defined as a delivery between 24 and 37 weeks
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Your previous pregnancy was complicated by premature rupture of membranes before 37 weeks
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You had a spontaneous second-trimester pregnancy loss between 14 and 24 weeks during previous pregnancy
To participate in this study, you may not meet one or more of the following criteria:
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You already use pro-, pre- or synbiotics
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You are pregnant with more than one baby
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You underwent a primary (type 1) cerclage (= a stitch through the cervix, which is placed to prevent the cervix from shortening and opening too early during pregnancy)
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You suffer from a disease in which the intestines are inflamed (e.g. Crohn's disease or ulcerative colitis)
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You have a known congenital uterine defect
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You have a history of cervical conization, a procedure in which a cone-shaped, abnormal piece of tissue is removed from the cervix
The investigator or study staff will discuss with you if you are eligible to participate into the study.